LeadersLee Bartel (PhD)
Institutions: Wasser Pain Management Centre Mount Sinai HospitalUniversity of Toronto, Faculty of MusicFred A Litwin and Family Centre in Genetic Medicine
Other members: Larry Picard (MD), Thenille Braun Janzen (PhD), Denise Paneduro (MA), Veronica Vuong (BMus), Marilyn Galonski (RN), Leah Pink (NP), Azar Azad (MLD, PhD), Ana Andreazza (PhD), Jed Meltzer (PhD), Hanna Faghfoury (MDCM, FRCPC)

Why was the study done?
Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder characterized by abnormally flexible joints, and is often accompanied by chronic pain. We planned to see if music and sound based low frequency vibrations can help reduce pain among hEDS patients.

How was the study done?
We conducted a study of 15 participants with hEDS and gave them sound vibration therapy. Participants took home a vibroacoustic device that plays music and produces vibration. They used this device 30 minutes a day 5 days per week over 4 weeks.

What were the study results?
Out of 14 patients that completed the study, 11 improved. We saw improvements in pain and improved mood. Many patients also noted that this had positive effects on their sleep and bowel movements. These results indicate promising preliminary results for sound based vibration therapy, a tool for managing pain related symptoms.

Recent Updates:

After an unusual amount of delay our Mechanisms of Fibromyalgia project cleared REB but is still paused due to COVID-19 but we are gearing up to start in January 2021 if possible. 

Last updated: January 2021

Selected Publications:
  • Vuong V, , Mosabbir A, Paneduro D, Gordon, A, Picard L, Faghfoury H, Chung S, Bartel L. The Effects of Rhythmic Sensory Stimulation on Hypermobile Ehlers-Danlos Syndrome: A Pilot Study. Pain Management and Research, 2019. (accepted)
  • Braun Janzen, Thenille, Paneduro, Denise, Picard, Denise, Gordon, Denise & Bartel, Lee R. (2019). A parallel randomized controlled trial examining the effects of rhythmic sensory stimulation on fibromyalgia symptoms. PLoS One 14(3): e0212021.